Ensartinib significantly prolonged progression-free survival, compared with crizotinib, in patients with ALK-positive non-small-cell lung cancer (NSCLC) in the eXalt3 study. Ensartinib, being developed by Xcovery Holdings, is a potent, next-generation, once-daily oral ALK inhibitor with broad preclinical activity against ALK-resistance mutations. “Its potency is more than 10 times greater than that of crizotinib in enzyme…
In the United States in recent years, mortality rates from the most common lung cancer, non-small cell lung cancer (NSCLC), have fallen sharply, due primarily to recent advances in treatment, said new study. The study was led by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health. “Reduced tobacco consumption…
Aspirin may decrease the risk of developing cancer, according to the study conducted by a binational team led by researchers at Massachusetts General Hospital (MGH), the Berman Center in Minnesota, and Monash University in Australia. Compelling evidence from clinical trials that included predominantly middle-aged adults demonstrates that aspirin may reduce the risk of developing cancer,…
Patients receiving interleukin-1£] (IL-1£]) inhibitors had lower rates of total hip or total knee replacements over an average follow up of 3.7 years, according to an exploratory analysis of data from the CANTOS (Canakinumab Anti-inflammatory Thrombosis Outcomes Study), which is a randomized double-blind, placebo-controlled trial. These findings are important, as no treatments currently exist that…
Highlights: World Hepatitis Day is celebrated annually on 28th July to create awareness on the global burden of viral hepatitis Around 290 million people are living with viral hepatitis unaware worldwide The theme for 2020 is ‘Find The Missing Millions’. World Hepatitis Day is celebrated annually on July 28th.Organizations around the world celebrate World Hepatitis…
The European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP) has given a thumbs up to two new oncology drugs. The Committee has recommended granting conditional marketing authorization for avapritinib (Ayvakit, Blueprint Medicines) for use in adults with unresectable or metastatic gastrointestinal stromal tumors (GIST) harboring a platelet-derived growth factor receptor alpha (PDGFRA) exon 18 mutation,…
Significant advances in the management of eye cancer mean that early referrals to subspecialists are crucial when ophthalmologists suspect disease in their patients, two leaders in the field say. “Don’t be afraid or embarrassed to contact an ocular oncologist,” said Carol Shields, MD, from Wills Eye Hospital in Philadelphia. Improvements in prognosis and treatment are…
As more jurisdictions mandate facial coverings in public, questions have arisen about whether it’s safe for everyone — including those with lung disease — to wear masks. Stories about people who claim to be unable to wear masks because of breathing problems are appearing in the news with increasing frequency, and patients are starting to call their…
As the world reels under the growing coronavirus cases, Russia’s Sechenov University has successfully completed the world’s first clinical trials of COVID-19 vaccine on humans. Chief researcher Elena Smolyarchuk, who heads the Center for Clinical Research on Medications at Sechenov University, told Russian news agency TASS on Sunday that the human trials for the vaccine…
